There is a scientific basis for “lower body thinking”: 92% of proteins are shared with the brain, and the organ workflow is similar

This article is from WeChat public number: quantum bit (ID: QbitAI), author: Yang Jing Bo Wen, original title: “lower body thinking” has a scientific basis! New research: 92% of proteins shared with the brain, organ workflow surprisingly similar”.

If there is an organ in the human body that is similar to the brain?

Well, stop. I know your answer.

Now, there is a scientific basis!

Scientists have recently discovered that there are more similarities between the testicles and the brain than you might think.

So much so, that the headline is so blunt.

Brain and testis: more alike than previously thought?

The findings were published in the journal Open Biology of the Royal Society.

There is a scientific basis for "lower body thinking": 92% of proteins are shared with the brain, and the organ workflow is similar

To what extent is it similar?

Probably, scanning the whole body organs, to do a series of, the two may be able to eliminate together.

In other words, except for the testicles, no other organ can be “eliminated” with the brain.

When this study came out, some people seemed to get some kind of true meaning.

That’s why it is called big head, small head…

There is a scientific basis for "lower body thinking": 92% of proteins are shared with the brain, and the organ workflow is similar

So, what kind of study is this?

Over 10,000 shared proteins
On a macro level, the testes and the brain don’t seem to be at all comparable.

Let’s say function.

One is responsible for thinking, whether it’s eating, drinking, or thinking about life, it has to pass through here.

One produces sperm and hormones, the source of millions of life every day, week after week, and life after life.

Structure words, emm …… will not elaborate.

There is a scientific basis for "lower body thinking": 92% of proteins are shared with the brain, and the organ workflow is similar

But it is such two seemingly unrelated organs that have always been somehow linked.

There have been some studies in the past that human intelligence, may be related to some semen quality parameters; the relationship between brain disorders and testicular dysfunction is also obvious ……

Only recently, scientists have found a plausible explanation for the similarities – they share more than 10,000 proteins.

What’s the concept?

Researchers compared proteins from 33 human tissues, including the heart, intestines, cervix, ovaries and placenta.

It turned out that the greatest number of proteins in common was observed between the brain and the testes.

Specifically, there are 14,315 proteins that make up the human brain and 15,687 that make up the testes, 13,442 of which are common to both tissues.

That is, the testis has over 85% of the same proteins as the brain. The percentage of proteins common to the brain, on the other hand, is even more than 92%.

There is a scientific basis for "lower body thinking": 92% of proteins are shared with the brain, and the organ workflow is similar

And furthermore, there are 5048 identical proteins between the neurons of the brain and the sperm of the testes.

There is a scientific basis for "lower body thinking": 92% of proteins are shared with the brain, and the organ workflow is similar

And many of these common proteins are associated with human tissue development, suggesting that both types of cells play an important role in human tissue development.

Presumably, these common proteins.

There is a scientific basis for "lower body thinking": 92% of proteins are shared with the brain, and the organ workflow is similar

Very high protein content, on the one hand, often results in “mutation on one side, damage on both sides”.

On the other hand, it also leads to a convergence in functional implementation.

Surprisingly similar workflows
The same protein types show similarities at the cellular and molecular level, and also indicate that the two organizations share a similar gene expression profile.

That is, they will perform many tasks in a very similar way: for example, astrocytes, also called astrocytes, in the brain will many times wrap around the synapses of neurons.

When performing cognitive functions, they convert glycogen to lactate, which is transported to neurons to supply energy to maintain synaptic activity.

There is a scientific basis for "lower body thinking": 92% of proteins are shared with the brain, and the organ workflow is similar

Similar to this are the supporting cells in the testes, responsible for providing protection and nutrition to the developing spermatozoa, and the various stages of sperm development occur on the surface of the supporting cells.

In order to produce the source of life, the supporting cells convert glucose into lactic acid, which is transported to the germ cells to supply energy to maintain the vital metabolism.

As you can see, in this one activity of metabolism, the cells of both tissues cooperate almost in one way.

In addition, neurons and sperm show similarities in the transport of substances.

They frequently release their own substances into the external environment, a process called cytokinesis.

Neurons achieve neurite growth by releasing neurotransmitters in a cytokinetic manner.

Sperm, on the other hand, release hydrolases and other important fertilization factors in order to reach the necessary conditions for fusion with the egg cell.

This process requires the transmission of signals, the more important of which is the calcium signal.

Neurons use calcium signals to regulate synaptic efficacy, secrete neurotransmitters, and control the excitability of neuronal membranes.

Sperm mobilize calcium signals to store the complex signals needed for the acrosome response, regulate movement, and ensure energy after ejaculation.

Functionally, calcium ions can be said to be the core of the same neuronal cells and sperm cells.

And these two tissues are also old “human” – even lymphocytes do not check these two parts when screening for foreign body invasion.

After all, they have a special mission and are highly sensitive to oxidative stress, so they are deserving of Immune Privilege.

Why are they so similar?
So, why are the brain and testes so similar?

Scientists say it may have something to do with human evolution.

The brain, placenta, and testes are all central players when it comes to speciation.

There is a scientific basis for "lower body thinking": 92% of proteins are shared with the brain, and the organ workflow is similar

While the role of the brain needs no introduction, the reproductive organs are the raw material for the evolution of the species.

What is the prerequisite for fertilization of the egg? There is a hero who runs away with a thousand horses and rolls away all his compatriots!

This competition between sperm is important for the formation of new species.

The “Chosen One” also vowed to defend territorial sovereignty, saying: I’m in, so all the other sperm can go to sleep.

This reproductive isolation barrier precludes gene flow between species and maintains the integrity of the species.

This also allowed genes related to brain and testicular function to change extraordinarily rapidly during human evolution, making them the two types of genes with the greatest interspecies variation.

Therefore, selective pressures to maintain interspecies variability may have acted more on these two organs, leading to their convergent evolution.

And they are very similar in terms of their expression patterns when it comes to passing on genes to offspring.

Mutations in the same protein or gene often cause neurological and testicular dysfunction.

The highest expression levels in the cerebral cortex and testes suggest that these genes may contribute to phenotypic traits unique to humans, such as increased cognitive abilities.

“Increased authenticity of emojis?”
In response to the study, the Sandy Network began by saying, regardless of national boundaries.

There is a scientific basis for "lower body thinking": 92% of proteins are shared with the brain, and the organ workflow is similar

△”The related expression package seems to have more weight yet ……”

And also some netizens issued a philosophical ♂ thinking.

As for the significance of this study, the researchers said

This is an unexplored topic, and we need to sort out the connections between these tissues, which will help understand diseases of brain and testicular function.

The paper is available at: https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.200322

Reference links: [1] https://phys.org/news/2021-06-human-brain-testis-highest-common.html%5B2%5D https://www.sciencealert.com/brains-and-testicles- have-more-in-common-with-one-another-than-you-ever-really-wanted-to-know

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